Pyxis Oncology Inc (PYXS)

Pyxis Oncology, Inc. is a clinical-stage biotechnology company focused on developing therapies for solid tumors. Its pipeline includes PYX-201, an antibody-drug conjugate in Phase 1 testing for patients with relapsed or refractory solid tumors, and PYX-106, a fully human IgG1 antibody targeting Siglec-15 that is also in Phase 1 development for advanced solid tumors. The company is further advancing PYX-107, a CD40 agonist with anti-cancer activity observed across several cancer indications, which is being studied in Phase 2 for tumor types including soft tissue sarcomas, esophageal and gastroesophageal junction cancers, and pancreatic ductal adenocarcinoma. Pyxis Oncology also has licensing arrangements with Pfizer and Biosion USA, Inc. to support development, manufacture, and commercialization of selected product candidates. Founded in 2018, the company is headquartered in Boston, Massachusetts.


Jump directly to the stock analysis sections supported by the latest available data.

Data update note: Fair value and stock analysis metrics are updated after regular market sessions when new data becomes available.
Ticker Fair Value Fair Value Upside/Downside Fair Value Rating Analyst Price Target Analyst Target Upside/Downside Analyst Target Rating Overall Financial Health Dividend Yield Next Earnings Date Price-to-Book Ratio Price-to-Sales Ratio Market Cap Enterprise Value Total Debt / Total Capital Free Float / Shares Outstanding Altman Z-Score Free Cash Flow / Net Income
NASDAQ-PYXS
$3.44
3.2% Upside
Fair
$8.44
153.6% Upside
Bargain
Fair
0.0%
November 17, 2026
24.3x
25.2x
277.7 M
262.6 M
5.9%
59.4%
-13.6
76.5%
Valuation • Fair Value

Pyxis Oncology Inc (NASDAQ-PYXS) Fair Value by Valuation Model

Review the available estimates for Pyxis Oncology Inc (NASDAQ-PYXS), including DCF Fair Value, Comps Fair Value.

Primary Valuation Read

Fair Value

$3.44

Estimated upside of 3.2% versus the current market price.

Fair Value Confidence

Low

Confidence level for the primary fair value estimate.

DCF Fair Value

$4.79

Discounted cash flow valuation reference.

Comps Fair Value

$2.89

Comparable-company valuation reference.

Analyst Price Target

$8.44

Analysts imply upside of 153.6%.

How to read these valuation models

Use the 5 available valuation references for Pyxis Oncology Inc (NASDAQ-PYXS) as analytical inputs, not a standalone conclusion. Valuation methods can differ because they rely on different assumptions, time horizons and financial inputs; compare the estimates with the current price and the company’s financial quality.

Profitability • Growth

Profitability & Growth for Pyxis Oncology Inc (NASDAQ-PYXS)

Review the profitability and growth indicators currently supported by the latest data.

Revenue

11.038 M

Current operating scale indicator.

Revenue Forecast

13.858 M

Forward revenue estimate.

EBITDA

-85.526 M

Current operating profitability reference.

How to read profitability and growth

This section helps investors review Pyxis Oncology Inc (NASDAQ-PYXS) from an operating perspective by combining current scale, forward revenue expectations and EBITDA-related profitability measures.

Quality • Risk

Quality & Financial Risk for Pyxis Oncology Inc (NASDAQ-PYXS)

Review the financial quality and risk indicators currently supported by the latest data.

Financial Health

Fair

Mixed or neutral financial-health read.

Piotroski Score

2

Weak quality score that deserves closer review.

Beneish M-Score

-3.32

No elevated caution signal from this screen.

Altman Z-Score

-13.6

Lower score that deserves closer risk review.

FCF / Net Income

76.5%

Cash conversion quality indicator.

How to read quality and risk

This section combines quality, balance-sheet and accounting-risk indicators for Pyxis Oncology Inc (NASDAQ-PYXS). Read the metrics together: no single score is a complete investment conclusion, but the combined view can highlight financial strength, earnings quality and areas that may deserve closer review.

Events • Dividends

Upcoming Events & Dividends for Pyxis Oncology Inc (NASDAQ-PYXS)

Track the upcoming dates and dividend metrics currently supported by the latest data.

Next Earnings Date

November 17, 2026

Days to Earnings

60

Dividend Yield

0.0%

No current dividend yield is indicated.

How to read events and dividends

This section helps investors track time-sensitive items for Pyxis Oncology Inc (NASDAQ-PYXS), including the next earnings date and dividend-related milestones. These items can matter for short-term volatility, income planning and event-driven positioning.

Stock Forecast • Technical Outlook

Pyxis Oncology Inc (NASDAQ-PYXS) Stock Forecast & Technical Outlook

Review Pyxis Oncology Inc (NASDAQ-PYXS) across multiple technical time frames, alongside analyst recommendation data, to form a faster read on market positioning and near-term sentiment.

Technical Signals by Time Frame

Switch between time frames to review the current technical signal for the stock.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: 15-minute • intraday
Strong Sell

The 15-minute technical read for Pyxis Oncology Inc (NASDAQ-PYXS) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: 1-hour • short-term
Strong Sell

The 1-hour technical read for Pyxis Oncology Inc (NASDAQ-PYXS) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: daily • daily
Neutral

The daily technical read for Pyxis Oncology Inc (NASDAQ-PYXS) is currently Neutral. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: weekly • weekly
Strong Buy

The weekly technical read for Pyxis Oncology Inc (NASDAQ-PYXS) is currently Strong Buy. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: monthly • monthly
Strong Buy

The monthly technical read for Pyxis Oncology Inc (NASDAQ-PYXS) is currently Strong Buy. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Analyst Consensus for Pyxis Oncology Inc (NASDAQ-PYXS)

A consolidated view of buy, hold and sell recommendations based on the currently available analyst data.

Strong Sell Sell Neutral Buy Strong Buy
Consolidated analyst recommendation mix
Strong Buy

Based on the available recommendation mix, Pyxis Oncology Inc (NASDAQ-PYXS) has a Strong Buy consensus, with 8 buy, 1 hold and 0 sell recommendations in the current data set.

Buy 8
Hold 1
Sell 0
FAQ Fast Investor Answers

Pyxis Oncology Inc (NASDAQ-PYXS) Stock FAQ

Data-supported answers about Pyxis Oncology Inc (NASDAQ-PYXS), including explicit coverage status where a reliable valuation estimate is not currently available.

Fair Value
$3.44
Estimated upside 3.2%
Valuation Rating
Undervalued
Estimated upside of 3.2%
Analyst Target
$8.44
Implied upside 153.6%
Financial Health
Fair
Current financial-health read

The current fair value estimate for Pyxis Oncology Inc (NASDAQ-PYXS) is $3.44. This implies an estimated upside of 3.2% versus the current market price.

Based on the current fair value estimate, the stock appears undervalued, with estimated upside of 3.2% versus the current market price.

The available analyst price target for Pyxis Oncology Inc (NASDAQ-PYXS) is $8.44. The analyst target implies estimated upside of 153.6%.

The current financial health read for Pyxis Oncology Inc (NASDAQ-PYXS) is Fair. This should be reviewed alongside valuation, profitability, debt and cash-flow quality metrics.

The next earnings date currently listed for Pyxis Oncology Inc (NASDAQ-PYXS) is November 17, 2026.

The latest available data indicates no current dividend yield for Pyxis Oncology Inc (NASDAQ-PYXS).

The current market capitalization listed for Pyxis Oncology Inc is 277.7 M.

The current enterprise value listed for Pyxis Oncology Inc is 262.6 M. Enterprise value can provide a broader valuation view than market capitalization alone because it also considers net debt.

The ticker symbol for Pyxis Oncology Inc is NASDAQ-PYXS, and the stock is listed on NASDAQ.

Pyxis Oncology Inc (NASDAQ-PYXS) is listed on NASDAQ.

The current debt-to-total-capital ratio listed for Pyxis Oncology Inc is 5.9%, which helps investors evaluate the company’s financing structure and leverage profile.

The free float listed for Pyxis Oncology Inc is 59.4%. Free float helps investors understand how much of the share base is available for public trading.