Sionna Therapeutics Inc (SION)

Sionna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for cystic fibrosis. Its pipeline includes several CFTR-targeted candidates, such as galicaftor (SION-2222) and navocaftor (SION-3067), both of which have completed Phase 2 trials, as well as SION-109 and SION-2851, which have each completed Phase 1 studies. The company is also advancing SION-451 in a Phase 1 trial and SION-719 in a Phase 2a proof-of-concept trial. Founded in 2019 and formerly known as Sling Therapeutics, Inc., Sionna Therapeutics is headquartered in Waltham, Massachusetts. Its common stock is listed on NASDAQ under the symbol SION.


Jump directly to the stock analysis sections supported by the latest available data.

Data update note: Fair value and stock analysis metrics are updated after regular market sessions when new data becomes available.
Ticker Fair Value Fair Value Upside/Downside Fair Value Rating Analyst Price Target Analyst Target Upside/Downside Analyst Target Rating Overall Financial Health Dividend Yield Next Earnings Date Price-to-Book Ratio Market Cap Enterprise Value Total Debt / Total Capital Free Float / Shares Outstanding Altman Z-Score Free Cash Flow / Net Income
NASDAQ-SION
$10.60
77.8% Upside
Bargain
$21
252.3% Upside
Bargain
Fair
0.0%
November 11, 2026
1.0x
269.5 M
9.282 M
2.4%
37.7%
9.2
78.3%
Valuation • Fair Value

Sionna Therapeutics Inc (NASDAQ-SION) Fair Value by Valuation Model

Review the available estimates for Sionna Therapeutics Inc (NASDAQ-SION), including Comps Fair Value.

Primary Valuation Read

Fair Value

$10.60

Estimated upside of 77.8% versus the current market price.

Fair Value Confidence

Very low

Confidence level for the primary fair value estimate.

Comps Fair Value

$10.60

Comparable-company valuation reference.

Analyst Price Target

$21

Analysts imply upside of 252.3%.

How to read these valuation models

Use the 4 available valuation references for Sionna Therapeutics Inc (NASDAQ-SION) as analytical inputs, not a standalone conclusion. Valuation methods can differ because they rely on different assumptions, time horizons and financial inputs; compare the estimates with the current price and the company’s financial quality.

Profitability • Growth

Profitability & Growth for Sionna Therapeutics Inc (NASDAQ-SION)

Review the profitability and growth indicators currently supported by the latest data.

Revenue Forecast

0 K

Forward revenue estimate.

EBITDA

-108.8 M

Current operating profitability reference.

EBITDA Forecast

-152.9 M

Forward operating profitability estimate.

How to read profitability and growth

This section helps investors review Sionna Therapeutics Inc (NASDAQ-SION) from an operating perspective by combining current scale, forward revenue expectations and EBITDA-related profitability measures.

Quality • Risk

Quality & Financial Risk for Sionna Therapeutics Inc (NASDAQ-SION)

Review the financial quality and risk indicators currently supported by the latest data.

Financial Health

Fair

Mixed or neutral financial-health read.

Piotroski Score

0

Weak quality score that deserves closer review.

Altman Z-Score

9.2

Relatively strong balance-sheet zone.

FCF / Net Income

78.3%

Cash conversion quality indicator.

How to read quality and risk

This section combines quality, balance-sheet and accounting-risk indicators for Sionna Therapeutics Inc (NASDAQ-SION). Read the metrics together: no single score is a complete investment conclusion, but the combined view can highlight financial strength, earnings quality and areas that may deserve closer review.

Events • Dividends

Upcoming Events & Dividends for Sionna Therapeutics Inc (NASDAQ-SION)

Track the upcoming dates and dividend metrics currently supported by the latest data.

Next Earnings Date

November 11, 2026

Days to Earnings

54

Dividend Yield

0.0%

No current dividend yield is indicated.

How to read events and dividends

This section helps investors track time-sensitive items for Sionna Therapeutics Inc (NASDAQ-SION), including the next earnings date and dividend-related milestones. These items can matter for short-term volatility, income planning and event-driven positioning.

Stock Forecast • Technical Outlook

Sionna Therapeutics Inc (NASDAQ-SION) Stock Forecast & Technical Outlook

Review Sionna Therapeutics Inc (NASDAQ-SION) across multiple technical time frames, alongside analyst recommendation data, to form a faster read on market positioning and near-term sentiment.

Technical Signals by Time Frame

Switch between time frames to review the current technical signal for the stock.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: 15-minute • intraday
Strong Sell

The 15-minute technical read for Sionna Therapeutics Inc (NASDAQ-SION) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: 1-hour • short-term
Strong Sell

The 1-hour technical read for Sionna Therapeutics Inc (NASDAQ-SION) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: daily • daily
Strong Sell

The daily technical read for Sionna Therapeutics Inc (NASDAQ-SION) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: weekly • weekly
Strong Sell

The weekly technical read for Sionna Therapeutics Inc (NASDAQ-SION) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Strong Sell Sell Neutral Buy Strong Buy
Time frame: monthly • monthly
Strong Sell

The monthly technical read for Sionna Therapeutics Inc (NASDAQ-SION) is currently Strong Sell. Use it as a timing signal only, and compare it with valuation, fundamentals and upcoming events before drawing a broader view.

Analyst Consensus for Sionna Therapeutics Inc (NASDAQ-SION)

A consolidated view of buy, hold and sell recommendations based on the currently available analyst data.

Strong Sell Sell Neutral Buy Strong Buy
Consolidated analyst recommendation mix
Hold

Based on the available recommendation mix, Sionna Therapeutics Inc (NASDAQ-SION) has a Hold consensus, with 2 buy, 10 hold and 0 sell recommendations in the current data set.

Buy 2
Hold 10
Sell 0
FAQ Fast Investor Answers

Sionna Therapeutics Inc (NASDAQ-SION) Stock FAQ

Data-supported answers about Sionna Therapeutics Inc (NASDAQ-SION), including explicit coverage status where a reliable valuation estimate is not currently available.

Fair Value
$10.60
Estimated upside 77.8%
Valuation Rating
Undervalued
Estimated upside of 77.8%
Analyst Target
$21
Implied upside 252.3%
Financial Health
Fair
Current financial-health read

The current fair value estimate for Sionna Therapeutics Inc (NASDAQ-SION) is $10.60. This implies an estimated upside of 77.8% versus the current market price.

Based on the current fair value estimate, the stock appears undervalued, with estimated upside of 77.8% versus the current market price.

The available analyst price target for Sionna Therapeutics Inc (NASDAQ-SION) is $21. The analyst target implies estimated upside of 252.3%.

The current financial health read for Sionna Therapeutics Inc (NASDAQ-SION) is Fair. This should be reviewed alongside valuation, profitability, debt and cash-flow quality metrics.

The next earnings date currently listed for Sionna Therapeutics Inc (NASDAQ-SION) is November 11, 2026.

The latest available data indicates no current dividend yield for Sionna Therapeutics Inc (NASDAQ-SION).

The current market capitalization listed for Sionna Therapeutics Inc is 269.5 M.

The current enterprise value listed for Sionna Therapeutics Inc is 9.282 M. Enterprise value can provide a broader valuation view than market capitalization alone because it also considers net debt.

The ticker symbol for Sionna Therapeutics Inc is NASDAQ-SION, and the stock is listed on NASDAQ.

Sionna Therapeutics Inc (NASDAQ-SION) is listed on NASDAQ.

The current debt-to-total-capital ratio listed for Sionna Therapeutics Inc is 2.4%, which helps investors evaluate the company’s financing structure and leverage profile.

The free float listed for Sionna Therapeutics Inc is 37.7%. Free float helps investors understand how much of the share base is available for public trading.