Spruce Biosciences Inc (SPRB)
Spruce Biosciences, Inc. is a biopharmaceutical company developing therapies for neurological disorders and other serious rare diseases. Its pipeline includes TA-ERT, an enzyme replacement therapy candidate for Sanfilippo Syndrome Type B, as well as Tildacerfont, which is being studied for a severe mental disorder marked by depressed mood and related cognitive, emotional, and physical symptoms. The company is also advancing SPR202 for Congenital Adrenal Hyperplasia, a chronic rare disease with no cure. Spruce Biosciences has a license agreement with Eli Lilly and Company covering research, development, and commercialization of certain pharmaceutical compounds, and a collaboration with Kaken Pharmaceutical Co. Ltd. focused on Tildacerfont for CAH in Japan. Incorporated in 2014, the company is headquartered in South San Francisco, California.
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| Ticker | Fair Value | Fair Value Upside/Downside | Fair Value Rating | Analyst Price Target | Analyst Target Upside/Downside | Analyst Target Rating | Overall Financial Health | Upcoming Dividend Ex-Date | Dividend Payment Date | Upcoming Dividend | Dividend Yield | Next Earnings Date | P/E Ratio | Price-to-Book Ratio | Price-to-Sales Ratio | Market Cap | Enterprise Value | Total Debt / Total Capital | Free Float / Shares Outstanding | Altman Z-Score | Payout Ratio | Free Cash Flow / Net Income |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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NASDAQ-SPRB
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$42.52
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-6.0% Downside
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Fair
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$151
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233.9% Upside
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Bargain
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Fair
|
—
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—
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—
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0.0%
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August 12, 2026
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-3.4x
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3.6x
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—
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122.5 M
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78.188 M
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5.5%
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96.4%
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-4.7
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—
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78.9%
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